Essential role of UCP1 modulating the central effects of thyroid hormones on energy balance

• Main Authors: Mayte Alvarez-Crespo (Author), Robert I. Csikasz (Author), Noelia Martínez-Sánchez (Author), Carlos Diéguez (Author), Barbara Cannon (Author), Jan Nedergaard (Author), Miguel López (Author)
• Format: Book
• Published: Elsevier, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Classically, metabolic effects of thyroid hormones (THs) have been considered to be peripherally mediated, i.e. different tissues in the body respond directly to thyroid hormones with an increased metabolism. An alternative view is that the metabolic effects are centrally regulated. We ha...