PODOCYTE-SPECIFIC OVEREXPRESSION OF SIRT-1 INCREASES NEPHRIN IN OBESE MICE FED A HIGH-FAT DIET

• Main Authors: Han Byoung-Geun (Author), Cui Jun (Author), Yang Jae-Won (Author), Choi Seung-Ok (Author)
• Format: Knjiga
• Izdano: The Korean Society of Nephrology, 2012-06-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Obesity can lead to inflammation, hyperlipidemia, diabetes, hypertension, and renal dysfunction, and is also associated with proteinuria. Histopathological changes in the glomeruli in obesity were characterized by glomerulomegaly and focal segmental glomerulosclerosis. This study was designed to inv...