Oridonin Delays Aging Through the AKT Signaling Pathway

• Egile Nagusiak: Yongpan An (Egilea), Jie Zhu (Egilea), Xin Wang (Egilea), Xinpei Sun (Egilea), Chunxiong Luo (Egilea), Yukun Zhang (Egilea), Yuwei Ye (Egilea), Xiaowei Li (Egilea), Abudumijiti Abulizi (Egilea), Zhizhen Huang (Egilea), Hang Zhang (Egilea), Baoxue Yang (Egilea), Zhengwei Xie (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Aging is a major risk factor for chronic diseases and disability in humans. Nowadays, no effective anti-aging treatment is available clinically. In this study, oridonin was selected based on the drug screening strategy similar to Connectivity MAP (CMAP) but upon transcriptomes of 102 traditional Chi...