Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting

• Автори: Liuxiang Chu (Автор), Aiping Wang (Автор), Ling Ni (Автор), Xiuju Yan (Автор), Yina Song (Автор), Mingyu Zhao (Автор), Kaoxiang Sun (Автор), Hongjie Mu (Автор), Sha Liu (Автор), Zimei Wu (Автор), Chunyan Zhang (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Glioblastoma is the most common malignant brain tumor. Efficient delivery of drugs targeting glioblastomas remains a challenge. Ephrin type-A receptor 3 (EPHA3) tyrosine kinase antibody-modified polylactide-co-glycolide (PLGA) nanoparticles (NPs) were developed to target glioblastoma via nose-to-bra...