Upregulation of the Creatine Transporter Slc6A8 by Klotho

• Main Authors: Ahmad Almilaji (Author), Mentor Sopjani (Author), Bernat Elvira (Author), José Borras (Author), Miribane Dërmaku-Sopjani (Author), Carlos Munoz (Author), Jamshed Warsi (Author), Undine E. Lang (Author), Florian Lang (Author)
• Format: Book
• Published: Karger Publishers, 2014-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: The transmembrane Klotho protein contributes to inhibition of 1,25(OH)2D3 formation. The extracellular domain of Klotho protein could function as an enzyme with e.g. β-glucuronidase activity, be cleaved off and be released into blood and cerebrospinal fluid. Klotho regulates several...