Reduced transcription of <it>TCOF1 </it>in adult cells of Treacher Collins syndrome patients

• Main Authors: Camargo Anamaria A (Author), Alonso Nivaldo (Author), Félix Têmis M (Author), Moura Ricardo (Author), Splendore-Gordonos Alessandra (Author), Ornelas Camila C (Author), Masotti Cibele (Author), Passos-Bueno Maria (Author)
• Format: Book
• Published: BMC, 2009-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Treacher Collins syndrome (TCS) is an autosomal dominant craniofacial disorder caused by frameshift deletions or duplications in the <it>TCOF1 </it>gene. These mutations cause premature termination codons, which are predi...