Dramatic improvement in dissolution rate of albendazole by a simple, one-step, industrially scalable technique

• Main Authors: Saeed Ghanbarzadeh (Author), Aram Khalili (Author), Abolghasem Jouyban (Author), Shahram Emami (Author), Yousef Javadzadeh (Author), Mohammad Solhi (Author), Hamed Hamishehkar (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Low solubility and dissolution rate are the primary challenges in the drug development which substantially impact the oral absorption and bioavailability of drugs. Due to the poor water solubility, Albendazole (ABZ) is poorly absorbed from the gastrointestinal tract and shows low oral bioavailabilit...