Protective Effects of p53 Regulatory Agents Against High-LET Radiation-Induced Injury in Mice

• Main Authors: Akinori Morita (Author), Bing Wang (Author), Kaoru Tanaka (Author), Takanori Katsube (Author), Masahiro Murakami (Author), Takashi Shimokawa (Author), Yuichi Nishiyama (Author), Shintaro Ochi (Author), Hidetoshi Satoh (Author), Mitsuru Nenoi (Author), Shin Aoki (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiation damage to normal tissues is one of the most serious concerns in radiation therapy, and the tolerance dose of the normal tissues limits the therapeutic dose to the patients. p53 is well known as a transcription factor closely associated with radiation-induced cell death. We recently demonst...