Targeting Herpes Simplex Virus-1 gD by a DNA Aptamer Can Be an Effective New Strategy to Curb Viral Infection

• Main Authors: Tejabhiram Yadavalli (Author), Alex Agelidis (Author), Dinesh Jaishankar (Author), Kyle Mangano (Author), Neel Thakkar (Author), Kumar Penmetcha (Author), Deepak Shukla (Author)
• Format: Book
• Published: Elsevier, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Herpes simplex virus type 1 (HSV-1) is an important factor for vision loss in developed countries. A challenging aspect of the ocular infection by HSV-1 is that common treatments, such as acyclovir, fail to provide effective topical remedies. Furthermore, it is not very clear whether the viral glyco...