Mineralocorticoid Receptor Signaling as a Therapeutic Target for Renal and Cardiac Fibrosis

• Κύριοι συγγραφείς: Greg H. Tesch (Συγγραφέας), Morag J. Young (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Activation of the mineralocorticoid receptor (MR) plays important roles in both physiological and pathological events. Blockade of MR signaling with MR antagonists (MRAs) has been used clinically to treat kidney and cardiac disease associated with hypertension and other chronic diseases, resulting i...