Dmdmdx/Largemyd: a new mouse model of neuromuscular diseases useful for studying physiopathological mechanisms and testing therapies

• Main Authors: Poliana C. M. Martins (Author), Danielle Ayub-Guerrieri (Author), Aurea B. Martins-Bach (Author), Paula Onofre-Oliveira (Author), Jackeline M. Malheiros (Author), Alberto Tannus (Author), Paulo L. de Sousa (Author), Pierre G. Carlier (Author), Mariz Vainzof (Author)
• Format: Book
• Published: The Company of Biologists, 2013-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Although muscular dystrophies are among the most common human genetic disorders, there are few treatment options available. Animal models have become increasingly important for testing new therapies prior to entering human clinical trials. The Dmdmdx mouse is the most widely used animal mode...