Chitosan/Cyclodextrin Nanospheres for Potential Nose-to-Brain Targeting of Idebenone
Idebenone (IDE) is a powerful antioxidant that is potentially active towards cerebral diseases, but its low water solubility and fast first pass metabolism reduce its accumulation in the brain, making it ineffective. In this work, we developed cyclodextrin-based chitosan nanospheres (CS NPs) as pote...
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MDPI AG,
2022-09-01T00:00:00Z.
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Internet
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A1234.567 |
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