Diminishment of Nrf2 Antioxidative Defense Aggravates Nephrotoxicity of Melamine and Oxalate Coexposure

• Main Authors: Chia-Fang Wu (Author), Chia-Chu Liu (Author), Yi-Chun Tsai (Author), Chu-Chih Chen (Author), Ming-Tsang Wu (Author), Tusty-Jiuan Hsieh (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic kidney disease (CKD) usually causes devastating healthy impacts on patients. However, the causes affecting the decline of kidney function are not fully revealed, especially the involvement of environmental pollutants. We have revealed that exposure to melamine, a ubiquitous chemical in daily...