Protective effect of guggulsterone against cardiomyocyte injury induced by doxorubicin in vitro

• Main Authors: Wang Wen-Ching (Author), Uen Yih-Huei (Author), Chang Ming-Long (Author), Cheah Khoot-Peng (Author), Li Joe-Sharg (Author), Yu Wen-Yu (Author), Lee Kock-Chee (Author), Choy Cheuk-Sing (Author), Hu Chien-Ming (Author)
• Format: Book
• Published: BMC, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Doxorubicin (DOX) is an effective antineoplastic drug; however, clinical use of DOX is limited by its dose-dependent cardiotoxicity. It is well known that reactive oxygen species (ROS) play a vital role in the pathological process of...