Global Sensitivity Analysis of Ventricular Myocyte Model-Derived Metrics for Proarrhythmic Risk Assessment
Multiscale computational models of the heart are being extensively investigated for improved assessment of drug-induced torsades de pointes (TdP) risk, a fatal side effect of many drugs. Model-derived metrics such as action potential duration and net charge carried by ionic currents (qNet) have been...
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| Main Authors: | , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2019-10-01T00:00:00Z.
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