Analysis of diagnostic test outcomes in a large loiasis cohort from an endemic region: Serological tests are often false negative in hyper-microfilaremic infections.

• Main Authors: Luzia Veletzky (Author), Kirsten Alexandra Eberhardt (Author), Jennifer Hergeth (Author), Daniel Robert Stelzl (Author), Rella Zoleko Manego (Author), Ruth Kreuzmair (Author), Gerrit Burger (Author), Johannes Mischlinger (Author), Matthew B B McCall (Author), Ghyslain Mombo-Ngoma (Author), Ayôla Akim Adegnika (Author), Selidji Todagbe Agnandji (Author), Pierre Blaise Matsiegui (Author), Bertrand Lell (Author), Peter Kremsner (Author), Benjamin Mordmüller (Author), Dennis Tappe (Author), Michael Ramharter (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>The parasitic disease loiasis is associated with significant morbidity and mortality. Individuals with hyper-microfilaremia (greater than 20,000 microfilariae per mL of blood) may suffer from serious treatment-related or spontaneous adverse events. Diagnosing loiasis r...