A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability
We previously described an in vitro single-chain fragment (scFv) library platform originally designed to generate antibodies with excellent developability properties. The platform design was based on the use of clinical antibodies as scaffolds into which replicated natural complementarity-determinin...
Saved in:
Main Authors: | Fortunato Ferrara (Author), Adeline Fanni (Author), Andre A. R. Teixeira (Author), Esteban Molina (Author), Camila Leal-Lopes (Author), Ashley DeAguero (Author), Sara D'Angelo (Author), M. Frank Erasmus (Author), Laura Spector (Author), Luis Antonio Rodriguez Carnero (Author), Jianquan Li (Author), Thomas J. Pohl (Author), Nikolai Suslov (Author), Klervi Desrumeaux (Author), Conor McMahon (Author), Sagar Kathuria (Author), Andrew R. M. Bradbury (Author) |
---|---|
Format: | Book |
Published: |
Taylor & Francis Group,
2024-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Determining the affinities of high-affinity antibodies using KinExA and surface plasmon resonance
by: M. Frank Erasmus, et al.
Published: (2023) -
Simultaneous affinity maturation and developability enhancement using natural liability-free CDRs
by: Andre A. R. Teixeira, et al.
Published: (2022) -
Pandemic's silver lining
by: Fortunato Ferrara, et al.
Published: (2022) -
Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody libraries
by: Andre Azevedo Reis Teixeira, et al.
Published: (2021) -
Interpretation of Metal Fab Drawings
by: Moran, Cameren
Published: (2021)