In Vitro Metabolism of Donepezil in Liver Microsomes Using Non-Targeted Metabolomics

• 主要な著者: Sin-Eun Kim (著者), Hyung-Ju Seo (著者), Yeojin Jeong (著者), Gyung-Min Lee (著者), Seung-Bae Ji (著者), So-Young Park (著者), Zhexue Wu (著者), Sangkyu Lee (著者), Sunghwan Kim (著者), Kwang-Hyeon Liu (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Donepezil is a reversible acetylcholinesterase inhibitor that is currently the most commonly prescribed drug for the treatment of Alzheimer's disease. In general, donepezil is known as a safe and well-tolerated drug, and it was not associated with liver abnormalities in several clinical trials....