Study protocol: DexaDays-2, hydrocortisone for treatment of dexamethasone-induced neurobehavioral side effects in pediatric leukemia patients: a double-blind placebo controlled randomized intervention study with cross-over design

• Main Authors: A. M. van Hulst (Author), E. J. Verwaaijen (Author), M. F. Fiocco (Author), S. M. F. Pluijm (Author), M. A. Grootenhuis (Author), R. Pieters (Author), E. L. T. van den Akker (Author), M. M. van den Heuvel-Eibrink (Author)
• Format: Book
• Published: BMC, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Dexamethasone, a highly effective drug in treating pediatric acute lymphoblastic leukemia (ALL), can induce serious neurobehavioral side effects. These side effects are experienced by patients and parents as detrimental with respect to health related quality of life (HRQoL). Base...