Celastrol slows the progression of early diabetic nephropathy in rats via the PI3K/AKT pathway

• Main Authors: Yusong Nie (Author), Chengxiao Fu (Author), Huimin Zhang (Author), Min Zhang (Author), Hui Xie (Author), Xiaopei Tong (Author), Yao Li (Author), Zhenyan Hou (Author), Xinrong Fan (Author), Miao Yan (Author)
• Format: Book
• Published: BMC, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Diabetic nephropathy serves as one of the most regular microvascular complications of diabetes mellitus and is the main factor that causes end-stage renal disease and incident mortality. As the beneficial effect and minute adverse influence of Celastrol on the renal system requir...