Dopamine D2 Receptor Activation Blocks GluA2/ROS Positive Feedback Loop to Alienate Chronic-Migraine-Associated Pain Sensitization

• Main Authors: Wei Zhang (Author), Xiaoyan Zhang (Author), Ming Lei (Author), Dunke Zhang (Author), Guangcheng Qin (Author), Jiying Zhou (Author), Lichun Ji (Author), Lixue Chen (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic migraine is a disabling disorder without effective therapeutic medicine. AMPA receptors have been proven to be essential to pathological pain and headaches, but the related regulatory mechanisms in chronic migraine have not yet been explored. In this study, we found that the level of surface...