Inhibit TGF-β1/Smad3 pathway by upregulation of miR145 with active vitamin D in lupus nephritis

Objective To investigate whether 1,25 (OH) 2D3 inhibits the TGF-β1/Smad3 pathway through upregulation of miR145 and its possible therapeutic mechanism in lupus nephritis. Methods A total of 42 8-week-old female ApoE-/- mice were divided into 7 groups of 6 mice each. Blank control group 1 and group 2...

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Main Authors: Tengjiao XU (Author), Xiaojie HE (Author), Xingyu MU (Author), Wei ZHANG (Author), Yan DING (Author)
Format: Book
Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology, 2022-12-01T00:00:00Z.
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