Inhibit TGF-β1/Smad3 pathway by upregulation of miR145 with active vitamin D in lupus nephritis

• Váldodahkkit: Tengjiao XU (Dahkki), Xiaojie HE (Dahkki), Xingyu MU (Dahkki), Wei ZHANG (Dahkki), Yan DING (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology, 2022-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Objective To investigate whether 1,25 (OH) 2D3 inhibits the TGF-β1/Smad3 pathway through upregulation of miR145 and its possible therapeutic mechanism in lupus nephritis. Methods A total of 42 8-week-old female ApoE-/- mice were divided into 7 groups of 6 mice each. Blank control group 1 and group 2...