Intermittent Hypoxia-Induced Renal Antioxidants and Oxidative Damage in Male Mice: Hormetic dose Response

• Main Authors: Weixia Sun (Author), Xia Yin (Author), Yuehui Wang (Author), Yi Tan (Author), Lu Cai (Author), Bo Wang (Author), Jun Cai (Author), Yaowen Fu (Author)
• Format: Book
• Published: SAGE Publishing, 2013-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obstructive sleep apnea causes cardiovascular disease via chronic intermittent hypoxia (IH), which may be related to oxidative stress. Nuclear factor-erythroid 2-related factor 2 (Nrf2) is an important cellular defense mechanism against oxidative stress by regulating its down-stream multiple antioxi...