A novel redox-responsive ursolic acid polymeric prodrug delivery system for osteosarcoma therapy

• Main Authors: Daijie Fu (Author), Zhe Ni (Author), Kerong Wu (Author), Peng Cheng (Author), Xiaofeng Ji (Author), Guoyuan Li (Author), Xifu Shang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ursolic acid (UA), found widely in nature, exerts effective anti-tumoral activity against various malignant tumors. However, the low water solubility and poor bioavailability of UA have greatly hindered its translation to the clinic. To overcome these drawbacks, a simple redox-sensitive UA polymeric...