Preparation, characterization, dissolution, and permeation of flibanserin − 2-HP-β-cyclodextrin inclusion complexes

• Główni autorzy: Adel F. Alghaith (Autor), Gamal M. Mahrous (Autor), Diaa Eldin Zidan (Autor), Nabil A. Alhakamy (Autor), Abdulmohsin J. Alamoudi (Autor), Awwad A. Radwan (Autor)
• Format: Książka
• Wydane: Elsevier, 2021-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Flibanserin (FLB), an antiserotonin drug, is used to treat women with hypoactive sexual appetite disorder. FLB shows low bioavailability (~33%) probably due to its low water solubility. The current study investigated the impact of hydroxypropyl-β-cyclodextrin (HP-β-CD) and sodium lauryl sulfate (SLS...