Preparation, characterization, dissolution, and permeation of flibanserin − 2-HP-β-cyclodextrin inclusion complexes

Preparation, characterization, dissolution, and permeation of flibanserin − 2-HP-β-cyclodextrin inclusion complexes

Flibanserin (FLB), an antiserotonin drug, is used to treat women with hypoactive sexual appetite disorder. FLB shows low bioavailability (~33%) probably due to its low water solubility. The current study investigated the impact of hydroxypropyl-β-cyclodextrin (HP-β-CD) and sodium lauryl sulfate (SLS...

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Main Authors: Adel F. Alghaith (Author), Gamal M. Mahrous (Author), Diaa Eldin Zidan (Author), Nabil A. Alhakamy (Author), Abdulmohsin J. Alamoudi (Author), Awwad A. Radwan (Author)
Format: Book
Published: Elsevier, 2021-09-01T00:00:00Z.
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