Preparation, characterization, dissolution, and permeation of flibanserin − 2-HP-β-cyclodextrin inclusion complexes

• Asıl Yazarlar: Adel F. Alghaith (Yazar), Gamal M. Mahrous (Yazar), Diaa Eldin Zidan (Yazar), Nabil A. Alhakamy (Yazar), Abdulmohsin J. Alamoudi (Yazar), Awwad A. Radwan (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Flibanserin (FLB), an antiserotonin drug, is used to treat women with hypoactive sexual appetite disorder. FLB shows low bioavailability (~33%) probably due to its low water solubility. The current study investigated the impact of hydroxypropyl-β-cyclodextrin (HP-β-CD) and sodium lauryl sulfate (SLS...