Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer

• Main Authors: Ali Mokhtar Mahmoud (Author), Magdalena Kostrzewa (Author), Viviana Marolda (Author), Marianna Cerasuolo (Author), Federica Maccarinelli (Author), Daniela Coltrini (Author), Sara Rezzola (Author), Arianna Giacomini (Author), Maria Pina Mollica (Author), Andrea Motta (Author), Debora Paris (Author), Antonio Zorzano (Author), Vincenzo Di Marzo (Author), Roberto Ronca (Author), Alessia Ligresti (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In spite of the huge advancements in both diagnosis and interventions, hormone refractory prostate cancer (HRPC) remains a major hurdle in prostate cancer (PCa). Metabolic reprogramming plays a key role in PCa oncogenesis and resistance. However, the dynamics between metabolism and oncogenesis are n...