The Transcription Factor Nrf2 Protects Angiogenic Capacity of Endothelial Colony-Forming Cells in High-Oxygen Radical Stress Conditions

• Autori principali: Hendrik Gremmels (Autore), Olivier G. de Jong (Autore), Diënty H. Hazenbrink (Autore), Joost O. Fledderus (Autore), Marianne C. Verhaar (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2017-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background. Endothelial colony forming cells (ECFCs) have shown a promise in tissue engineering of vascular constructs, where they act as endothelial progenitor cells. After implantation, ECFCs are likely to be subjected to elevated reactive oxygen species (ROS). The transcription factor Nrf2 regula...