New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases

• Main Authors: Yosselin Huentupil (Author), Luis Peña (Author), Néstor Novoa (Author), Emanuela Berrino (Author), Rodrigo Arancibia (Author), Claudiu T. Supuran (Author)
• 格式: 图书
• 出版: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

A series of organometallic acylhydrazones was prepared, incorporating Re(CO)3, Mn(CO)3 and ferrocenyl moieties, which were subsequently reacted with amino-sulfonamides in order to obtain carbonic anhydrase (CA, EC 4.2.1.1) inhibitors possessing organometallic moieties in their molecules. The new der...