P-Glycoprotein-Evading Anti-tumor Activity of a Novel Tubulin and HSP90 Dual Inhibitor in a Non-small-cell Lung Cancer Model

P-glycoprotein (P-gp)-induced drug resistance is a major road block for successful cancer chemotherapy. Through phenotypic screening, the compound 2-(2-chlorophenylimino)-5-(4-dimethylaminobenzylidene)thiazolidin-4-one (CDBT) was discovered to have potent antitumor activity in P-gp over-expressing d...

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Main Authors: Qiu Zhang (Author), Shumei Zhai (Author), Liwen Li (Author), Xiue Li (Author), Cuijuan Jiang (Author), Chengke Zhang (Author), Bing Yan (Author)
Format: Book
Published: Elsevier, 2014-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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