P-Glycoprotein-Evading Anti-tumor Activity of a Novel Tubulin and HSP90 Dual Inhibitor in a Non-small-cell Lung Cancer Model
P-glycoprotein (P-gp)-induced drug resistance is a major road block for successful cancer chemotherapy. Through phenotypic screening, the compound 2-(2-chlorophenylimino)-5-(4-dimethylaminobenzylidene)thiazolidin-4-one (CDBT) was discovered to have potent antitumor activity in P-gp over-expressing d...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2014-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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