Tumor containing fragment number influences immunohistochemistry positive rate of HER2 in biopsy specimens of gastric cancer

• Main Authors: Chen Xu (Author), Yalan Liu (Author), Xiaowen Ge (Author), Dongxian Jiang (Author), Ying Zhang (Author), Yuan Ji (Author), Jun Hou (Author), Jie Huang (Author), Jieakesu Su (Author), Haiying Zeng (Author), Jing Qin (Author), Yingyong Hou (Author)
• Format: Book
• Published: BMC, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background HER2 assessment in biopsy specimens of gastric cancer (GC) is challenging because of the intratumoral heterogeneity. False negative results may be get because of limited biopsy material. The aim of this study is to explore how tumor-containing fragment number and biopsy specimen...