Knockdown of subunit 3 of the COP9 signalosome inhibits C2C12 myoblast differentiation via NF-KappaB signaling pathway

• Auteurs principaux: Mariam A. Ba (Auteur), Jeffrey Surina (Auteur), Cherie A. Singer (Auteur), Maria L. Valencik (Auteur)
• Format: Livre
• Publié: BMC, 2017-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background The COP9 signalosome (CSN) is a conserved protein complex composed of 8 subunits designated CSN1-CSN8. CSN3 represents the third subunit of the CSN and maintains the integrity of the complex. CSN3 binds to the striated muscle-specific β1D integrin tail, and its subcellular locali...