Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles

• Hlavní autoři: Guo‐Kai Shang (Autor), Lu Han (Autor), Zhi‐Hao Wang (Autor), Ya‐Peng Liu (Autor), Sen‐Bo Yan (Autor), Wen‐Wen Sai (Autor), Di Wang (Autor), Yi‐Hui Li (Autor), Wei Zhang (Autor), Ming Zhong (Autor)
• Médium: Kniha
• Vydáno: Wiley, 2020-08-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract Background Sarcopenia causes several adverse events in elderly people. Muscle fibre atrophy and interstitial fibrosis are the main histopathological changes in sarcopenia and account for decreased muscle function. Tribbles homologue 3 (TRB3) was previously reported to exhibit age‐related ex...