Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variant

• Asıl Yazarlar: Lucie Yammine (Yazar), Belén Picatoste (Yazar), Nazish Abdullah (Yazar), Rosemary A. Leahey (Yazar), Emma F. Johnson (Yazar), Nicolás Gómez-Banoy (Yazar), Carolina Rosselot (Yazar), Jennifer Wen (Yazar), Tahmina Hossain (Yazar), Marcus D. Goncalves (Yazar), James C. Lo (Yazar), Adolfo Garcia-Ocaña (Yazar), Timothy E. McGraw (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2023-12-01T00:00:00Z.
• Konular: article
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Objective: Glucose-dependent insulinotropic polypeptide (GIP) has a role in controlling postprandial metabolic tone. In humans, a GIP receptor (GIPR) variant (Q354, rs1800437) is associated with a lower body mass index (BMI) and increased risk for Type 2 Diabetes. To better understand the impacts of...