Vulnerability of Triple-Negative Breast Cancer to Saponin Formosanin C-Induced Ferroptosis

• Автори: Hsin-Chih Chen (Автор), Han-Hsuan Tang (Автор), Wei-Hsiang Hsu (Автор), Shan-Ying Wu (Автор), Wen-Hsing Cheng (Автор), Bao-Yuan Wang (Автор), Chun-Li Su (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Targeting ferritin via autophagy (ferritinophagy) to induce ferroptosis, an iron- and reactive oxygen species (ROS)-dependent cell death, provides novel strategies for cancer therapy. Using a ferroptosis-specific inhibitor and iron chelator, the vulnerability of triple-negative breast cancer (TNBC)...