Folate receptor-targeted mixed polysialic acid micelles for combating rheumatoid arthritis: in vitro and in vivo evaluation

• Main Authors: Nan Zhang (Author), Chunyu Xu (Author), Na Li (Author), Shasha Zhang (Author), Lingling Fu (Author), Xiao Chu (Author), Haiying Hua (Author), Xianghui Zeng (Author), Yongxing Zhao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Rheumatoid arthritis (RA) is associated with chronic inflammation. The suppression of inflammation is key to the treatment of RA. Glucocorticoids (GCs) are classical anti-inflammatory drugs with several disadvantages such as poor water solubility and low specificity in the body. These dis...