Potential of the Trifunctional Bispecific Antibody Surek Depends on Dendritic Cells: Rationale for a New Approach of Tumor Immunotherapy

• Главные авторы: Nina Eissler (Автор), Josef Mysliwietz (Автор), Nina Deppisch (Автор), Peter Ruf (Автор), Horst Lindhofer (Автор), Ralph Mocikat (Автор)
• Формат: ‌
• Опубликовано: BMC, 2013-03-01T00:00:00Z.
• Предметы: article
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Abstract Trifunctional bispecific antibodies (trAbs) used in tumor immunotherapy have the unique ability to recruit T cells toward antigens on the tumor cell surface and, moreover, to activate accessory cells through their immunoglobulin Fc region interacting with activating Fcγ receptors. This scen...