Correlation of plasma cell assessment by phenotypic methods and molecular profiles by NGS in patients with plasma cell dyscrasias

• Main Authors: Ekaterina Rebmann Chigrinova (Author), Naomi A. Porret (Author), Martin Andres (Author), Gertrud Wiedemann (Author), Yara Banz (Author), Myriam Legros (Author), Matthias Pollak (Author), Elisabeth Oppliger Leibundgut (Author), Thomas Pabst (Author), Ulrike Bacher (Author)
• Format: Book
• Published: BMC, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Next-generation sequencing (NGS) detects somatic mutations in a high proportion of plasma cell dyscrasias (PCD), but is currently not integrated into diagnostic routine. We correlated NGS data with degree of bone marrow (BM) involvement by cytomorphology (BMC), histopathology (BM...