Evaluation of Alectinib Metabolic Stability in HLMs Using Fast LC-MS/MS Method: In Silico ADME Profile, P450 Metabolic Lability, and Toxic Alerts Screening

• Asıl Yazarlar: Mohamed W. Attwa (Yazar), Haitham AlRabiah (Yazar), Gamal A. E. Mostafa (Yazar), Adnan A. Kadi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Alectinib, also known as Alecensa^®, is prescribed for the therapeutic treatment of individuals diagnosed with metastatic non-small cell lung cancer (NSCLC) who have a specific genetic mutation referred to as anaplastic lymphoma kinase (ALK) positivity. The Food and Drug Admini...