The Common Haplotype GATGACA in Surfactant-Protein B Gene Is Protective for Respiratory Distress Syndrome in Preterm Neonates

• Main Authors: Silvia Mikolajcikova (Author), Zora Lasabova (Author), Veronika Holubekova (Author), Maria Skerenova (Author), Jana Zibolenova (Author), Katarina Matasova (Author), Mirko Zibolen (Author), Andrea Calkovska (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundRespiratory distress syndrome (RDS), a disorder of primary surfactant deficiency resulting in pulmonary insufficiency, remains a significant problem for preterm neonates. Associations between genetic variants of surfactant proteins and RDS have been reported, but haplotypes of the surfacta...