Continuous enzyme activity assay for high-throughput classification of histone deacetylase 8 inhibitors
Aim: Human histone deacetylase 8 (KDAC8) is a well-recognized pharmaceutical target in Cornelia de Lange syndrome and different types of cancer, particularly childhood neuroblastoma. Several classes of chemotypes have been identified, which interfere with the enzyme activity of KDAC8. These compound...
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Format: | Book |
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Open Exploration Publishing Inc.,
2023-06-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |