Transport and metabolism at blood-brain interfaces and in neural cells: relevance to bilirubin-induced encephalopathy
Bilirubin, the end-product of heme catabolism, circulates in non pathological plasma mostly as a protein-bound species. When bilirubin concentration builds up, the free fraction of the molecule increases. Unbound bilirubin then diffuses across blood-brain interfaces into the brain, where it accumula...
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| Main Authors: | , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2012-05-01T00:00:00Z.
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