Mesenchymal Stem Cell-Secreted TGF-β1 Restores Treg/Th17 Skewing Induced by Lipopolysaccharide and Hypoxia Challenge via miR-155 Suppression

• Váldodahkkit: Ming Xue (Dahkki), Xiwen Zhang (Dahkki), Jianxiao Chen (Dahkki), Feng Liu (Dahkki), Jingyuan Xu (Dahkki), Jianfeng Xie (Dahkki), Yi Yang (Dahkki), Weiping Yu (Dahkki), Haibo Qiu (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2022-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background. Regulatory T cell (Treg)/T helper (Th) 17 skewing is important in the development of acute respiratory distress syndrome (ARDS). Immunomodulatory effects of mesenchymal stem cell- (MSC-) secreted transforming growth factor- (TGF-) β1 on CD4+ T cells are environment-sensitive and lack dis...