Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study

• Main Authors: Xiaoyu Li (Author), Xiaojiaoyang Li (Author), Junxian Lu (Author), Youyi Huang (Author), Lili Lv (Author), Yongfu Luan (Author), Runping Liu (Author), Rong Sun (Author)
• Format: Book
• Published: BMC, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Radix Bupleuri (RB) has been popularly used for treating many liver diseases such as chronic hepatic inflammation and viral Hepatitis in China. Increasing clinical and experimental evidence indicates the potential hepatotoxicity of RB or prescriptions containing RB. Recently, Sai...