Integrin α11β1 is expressed in breast cancer stroma and associates with aggressive tumor phenotypes

• Main Authors: Hilde Ytre‐Hauge Smeland (Author), Cecilie Askeland (Author), Elisabeth Wik (Author), Gøril Knutsvik (Author), Anders Molven (Author), Reidunn J Edelmann (Author), Rolf K Reed (Author), David J Warren (Author), Donald Gullberg (Author), Linda Stuhr (Author), Lars A Akslen (Author)
• Format: Book
• Published: Wiley, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Cancer‐associated fibroblasts are essential modifiers of the tumor microenvironment. The collagen‐binding integrin α11β1 has been proposed to be upregulated in a pro‐tumorigenic subtype of cancer‐associated fibroblasts. Here, we analyzed the expression and clinical relevance of integrin α11...