Prediction of Human Pharmacokinetics of Antibody-Drug Conjugates From Nonclinical Data

Prediction of human pharmacokinetics (PK) based on preclinical information for antibody-drug conjugates (ADCs) provide important insight into first‐in‐human (FIH) study design. This retrospective analysis was conducted to identify an appropriate scaling method to predict human PK for ADCs from anima...

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Main Authors: Chunze Li (Author), Cindy Zhang (Author), Rong Deng (Author), Douglas Leipold (Author), Dongwei Li (Author), Brandon Latifi (Author), Yuying Gao (Author), Crystal Zhang (Author), Zao Li (Author), Dale Miles (Author), Shang‐Chiung Chen (Author), Divya Samineni (Author), Bei Wang (Author), Priya Agarwal (Author), Dan Lu (Author), Saileta Prabhu (Author), Sandhya Girish (Author), Amrita V. Kamath (Author)
פורמט: ספר
יצא לאור: Wiley, 2019-09-01T00:00:00Z.
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סימן המיקום: A1234.567
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