Risk factors for antibiotic resistance in <it>Campylobacter </it>spp. isolated from raw poultry meat in Switzerland
<p>Abstract</p> <p>Background</p> <p>The world-wide increase of foodborne infections with antibiotic resistant pathogens is of growing concern and is designated by the World Health Organization as an emerging public health problem. Thermophilic <it>Campylobacter &...
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BMC,
2003-12-01T00:00:00Z.
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| Summary: | <p>Abstract</p> <p>Background</p> <p>The world-wide increase of foodborne infections with antibiotic resistant pathogens is of growing concern and is designated by the World Health Organization as an emerging public health problem. Thermophilic <it>Campylobacter </it>have been recognised as a major cause of foodborne bacterial gastrointestinal human infections in Switzerland and in many other countries throughout the world. Poultry meat is the most common source for foodborne cases caused by <it>Campylobacter</it>. Because all classes of antibiotics recommended for treatment of human campylobacteriosis are also used in veterinary medicine, in view of food safety, the resistance status of <it>Campylobacter </it>isolated from poultry meat is of special interest.</p> <p>Methods</p> <p>Raw poultry meat samples were collected throughout Switzerland and Liechtenstein at retail level and examined for <it>Campylobacter </it>spp. One strain from each <it>Campylobacter</it>-positive sample was selected for susceptibility testing with the disc diffusion and the E-test method. Risk factors associated with resistance to the tested antibiotics were analysed by multiple logistic regression.</p> <p>Results</p> <p>In total, 91 <it>Campylobacter </it>spp. strains were isolated from 415 raw poultry meat samples. Fifty-one strains (59%) were sensitive to all tested antibiotics. Nineteen strains (22%) were resistant to a single, nine strains to two antibiotics, and eight strains showed at least three antibiotic resistances. Resistance was observed most frequently to ciprofloxacin (28.7%), tetracycline (12.6%), sulphonamide (11.8%), and ampicillin (10.3%). One multiple resistant strain exhibited resistance to five antibiotics including ciprofloxacin, tetracycline, and erythromycin. These are the most important antibiotics for treatment of human campylobacteriosis. A significant risk factor associated with multiple resistance in <it>Campylobacter </it>was foreign meat production compared to Swiss meat production (odds ratio = 5.7).</p> <p>Conclusion</p> <p>Compared to the situation in other countries, the data of this study show a favourable resistance situation for <it>Campylobacter </it>strains isolated from raw poultry meat produced in Switzerland. Nevertheless, the prevalence of 19% ciprofloxacin resistant strains is of concern and has to be monitored. "Foreign production vs. Swiss production" was a significant risk factor for multiple resistance in the logistic regression model. Therefore, an adequate resistance-monitoring programme should include meat produced in Switzerland as well as imported meat samples.</p> |
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| Item Description: | 10.1186/1471-2458-3-39 1471-2458 |