Production of Cloned Pigs Derived from Double Gene Knockout Cells Using CRISPR/Cas9 System and MACS-based Enrichment System

• Main Authors: Bumrae Cho (Author), Su Jin Kim (Author), Eun-Jin Lee (Author), Sun Mi Ahn (Author), Jin Seok Lee (Author), Dal-young Ji (Author), Sang Hoon Lee (Author), Jung-Taek Kang (Author)
• Format: Book
• Published: The Korean Society of Animal Reproduction and Biotechnology, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pigs are considered as optimal donor animal for the successful xenotransplantation. To increase the possibility of clinical application, genetic modification to increase compatibility with human is an important and essential process. Genetic modification technique has been developed and improved to...