Population Pharmacokinetics of Primaquine in the Korean Population

• Main Authors: Woo-Yul Lee (Author), Dong-Woo Chae (Author), Choon-Ok Kim (Author), Sang-Eun Lee (Author), Yee-Gyung Kwak (Author), Joon-Sup Yeom (Author), Kyung-Soo Park (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

While primaquine has long been used for malaria treatment, treatment failure is common. This study aims to develop a population pharmacokinetic model of primaquine and its metabolite, carboxyprimaquine, and examine factors influencing pharmacokinetic variability. The data was obtained from a clinica...