NVP-BEZ235 Inhibits Renal Cell Carcinoma by Targeting TAK1 and PI3K/Akt/mTOR Pathways

In spite of the promising in vitro and preclinical results, dual PI3K/Akt/mTOR inhibitor NVP-BEZ235, and ATP-competitive mTOR inhibitor PP242 both failed to confirm their inhibitory efficacy against renal cell carcinoma (RCC) in clinical settings. Therefore, a better understanding of the molecular m...

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Main Authors: Bihui Li (Author), Xing Zhang (Author), Qianyao Ren (Author), Li Gao (Author), Jing Tian (Author)
Format: Book
Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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